Public Health
by Joan B. Rose, PhD, and Ralph Morris, MD, MPH
Virus-Associated Mystery Syndrome on the Rise: Acute Flaccid Myelitis
Named for its symptoms, acute flaccid myelitis (AFM) is a polio-like, paralyzing neurological condition that primarily afflicts young children aged 2 to 8 years. Although very rare, confirmed cases of AFM have spiked sharply since 2014, when the Centers for Disease Control and Prevention (CDC) first noted the increase (see box). Available clinical, laboratory, and other evidence all suggest a viral association, and over 90% of confirmed cases had a mild respiratory illness or fever consistent with a viral infection before developing AFM. CDC is working closely with healthcare providers as well as state and local health departments to investigate and confirm AFM cases, including possible causes, risk factors, and potential treatment options. Yet because much about AFM remains a mystery—including why a small but growing number of people develop AFM after a viral infection while most others recover—some parents and doctors have grown impatient with CDC....
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